The active ingredient of
Ovaplant is the analogue of salmon GnRH or sGnRHa. The native peptide is
released from brain cells of the hypothalamus that then bind to receptors on
pituitary cells. The sGnRHa in Ovaplant acts in this fashion except that
- it travels to the pituitary from the
pellet through the blood,
- it is present in greater than
physiological amounts and
- binds to the pituitary receptors with a
greater affinity than native peptide and hence is more potent.
These three factors, external source, greater
availability and greater potency, induce and increase a continued liberation
of maturational hormones from the pituitary. These pituitary hormones elicit
gonad maturation together with the constituent and complementary hormone
production from the gonads. The result is the earlier, complete production
of viable eggs and milt.
Applications
Ovaplant can be used in a population of fish with a well-defined breeding
or spawning period. Ovaplant can advance maturation dates by weeks in most
populations with a uniform and short spawning period. In other cases,
Ovaplant can move spawning dates forward by appreciable amounts. When used
in the normal spawning season, using Ovaplant can compress the spawning
season to maximize spawning potential and conserve resources. Ovaplant can
also be used in fish that have been photoperiod controlled. There is no
substitute for well-described broodstock performance and the best results
for using Ovaplant are in stocks with a recorded spawning history.
Typical uses
There are four main uses of Ovaplant:
- To advance spawning date in a population.
An advanced spawning date gives producers a greater flexibility in
marketing ova and offspring. It also has many beneficial downstream
effects that are realized when spawning is confined to a predictable and
defined period.
- To compress the spawning season. Often
fish in a population will spawn over a protracted period. Ovaplant can
compress and shorten the spawning season that permits optimization of
time and resources.
- To restart stalled maturation. Sometimes
handling or other stress causes valuable broodstock to stop maturing
after the process has begun. Ovaplant can help to restart maturation in
a natural way without effecting gamete viability.
- To increase milt production. Chronic
problems of milt shortages are commonplace in aquaculture. This may
disrupt detailed breeding programs. Ovaplant serves to increase milt
production and lengthen the time males will produce.
Species list
Ovaplant can be used in all species of fish.
The forms of GnRH that naturally occur in the brains of fishes differ
throughout the more than 25,000 fish species. However, the salmon form of
GnRH is present in most of these fish and thus the sGnRHa in Ovaplant is the
peptide of choice. Among the other types of GnRH found in the other fishes,
there is such a conservation of form and function that Ovaplant works
successfully. For specific application of Ovaplant to your fish, consult
Syndel Labs.
Critical Requirements
It is primary important that the protocols of
Ovaplant be used for successful results. Paramount is defining the intended
purpose: advanced maturation, compressed spawning, re-starting maturation or
increased milt production. In each of these applications the timing of
Ovaplant use differs. Generally, the closer to normal spawning date that
Ovaplant is used, the greater the success.
Another consideration is sample size. Fish
spawn in a season that may span weeks or months. By implanting only a few
fish from a population, it is equally likely that late and early spawning
fish could be chosen. This would give results concomitant with the
reproductive state in individual fish: all fish would spawn earlier than
normal (eg weeks earlier), but it would be impossible to determine which
fish were moved forward the most or at all. The solution is to try Ovaplant
on a larger sample of fish with a well-defined history of spawning dates.
Packaging and Presentation
Ovaplant comes in a cassette that contains 24
implants. The cassettes fit into an implanting gun that is easy to use and
is autoclavable. The removable implanting needles are disposable and can be
sterilized. Simply insert the needle, pull the trigger and withdraw the
needle. The implants contain enough sGnRHa to accommodate a range of fish
weights with a wide range of therapeutic efficacy. |